HIGHLIGHTS
- who: Alice Lepelley from the Université de Paris, Imagine Institute, Laboratory of Neurogenetics and Neuroinflammation, Inserm UMR, Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom have published the paper: Mitochondrial Nucleic Acid as a Driver of Pathogenic Type I Interferon Induction in Mendelian Disease, in the Journal: (JOURNAL)
- what: In this review the authors focus on mtNA cytosolic sensing leading to IFN induction.
SUMMARY
Strikingly, the majority of type I interferonopathy-related disease genes identified to date encode molecules playing a role in nucleic_acid processing . . .
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