Mitochondrial oxidative phosphorylation is dispensable for survival of cd34+ chronic myeloid leukemia stem and progenitor cells

HIGHLIGHTS

• who: Jin-Song Yan from the Patients and cells Bone marrow samples were collected from , cases of newly diagnosed CML patients at the Department of Hematology of the Second Hospital of Dalian Medical UniversityPatients were diagnosed according to French-American-British classification. Informed consent was obtained from all patients in accordance with the Declaration of Helsinki, and all manipulations were approved by the Medical Science Ethic Committee of Dalian Medical University. Mononuclear cells were isolated by density gradient centrifugation using Lymphoprep, and cryopreserved. In addition, potential donors for allogeneic bone marrow transplantation were used to purify healthy . . .
  

   

  

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