Mitochondrial protein synthesis is essential for terminal differentiation of cd45- ter119-erythroid and lymphoid progenitors

HIGHLIGHTS

  • who: Kazuhito Gotoh from the Kyushu University have published the paper: Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45- TER119-Erythroid and Lymphoid Progenitors, in the Journal: (JOURNAL) of November/20,/2020
  • what: The authors have shown that mitochondrial p32/C1qbp is essential for terminal differentiation of CD51- TNCs into erythrocytes and B-lymphocytes. In the aspect of mechanisms, the authors focused on the CD51- TNCs.
  • how: These results indicated that synthesis of proteins associated with the mitochondrial respiratory_chain was dependent on p32/C1qbp in hematopoietic cells which prompted the authors . . .

     

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