HIGHLIGHTS
- who: Yu Chen from the DepartmentChongqing University University, Chongqing, China have published the research: Mitochondrial pyruvate carrier: a metabolic-epigenetic checkpoint orchestrating T cell differentiation, in the Journal: (JOURNAL) of 11/06/2022
SUMMARY
Received Mitochondrial pyruvate carrier: a metabolic-epigenetic checkpoint... Chen et_al the mitochondrial function and pyruvate metabolic pathway. In addition to be derived from glutamine oxidation and FAO, acetyl-CoA can be produced from other alternative pathways which may also partially regulate T_cell differentiation. Of note, MPC transient inhibitor UK5099 is also an inhibitor of monocarboxylate transporter (MCT), its side . . .
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