Mitocore: a curated constraint-based model for simulating human central metabolism

HIGHLIGHTS

  • who: Anthony C. Smith from the Medical Research Council Biology Unit, University of UK have published the research: MitoCore: a curated constraint-based model for simulating human central metabolism, in the Journal: (JOURNAL)
  • what: This model has been designed to be easy-to-use, includes extensive annotation, has default parameters to simulate human cardiomyocyte metabolism, and is encoded in the widely used SBML format . To facilitate gene-based analyses (such as knock out studies) the authors provide reaction-to-gene mappings with both gene symbols and Ensembl identifiers. To determine the robustness of the model . . .

     

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