Mitofilin mitigates myocardial damage in acute myocardial infarction by regulating pyroptosis of cardiomyocytes

HIGHLIGHTS

  • who: Yong He from the Department of Cardiology, West China, Sichuan University, Chengdu, China, Department of Cardiology, The Sixth have published the research work: Mitofilin Mitigates Myocardial Damage in Acute Myocardial Infarction by Regulating Pyroptosis of Cardiomyocytes, in the Journal: (JOURNAL)
  • what: The authors established a mouse model of AMI with adenovirus-mediated mitofilin overexpression and examined the role of mitofilin in cellular damages and pyroptosis in AMI.
  • how: Downregulation of Mitofilin Expression in AMI Mice Adenovirus Production and Transduction Into Cardiomyocytes in_vivo To evaluate the potential role of mitofilin in AMI the . . .

     

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