HIGHLIGHTS
- who: Arnaud Mary from the (UNIVERSITY) have published the paper: Mitophagy in Alzheimeru2812s disease: Molecular defects and therapeutic approaches, in the Journal: (JOURNAL) of 18/01/2022
- what: The authors provide insights into the specific impact of different actors implicated in AD etiology, including Tau, APOE4, presenilin 1 (PS1), APP-derived fragments (Au03b2 and APP C-terminal fragments: APP-CTFs) on mitophagy processes (Fig 2B).
- how: This review discusses studies examining the status of mitophagy in AD patients as well as in various in_vitro and in_vivo AD models.
SUMMARY
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