Mks-nphp module proteins control ciliary shedding at the transition zone

HIGHLIGHTS

• who: Delphine Gogendeau and collaborators from the Institut de Biologie Paris-Seine (IBPS), Paris, France have published the article: MKS-NPHP module proteins control ciliary shedding at the transition zone, in the Journal: (JOURNAL) of March/12,/2020
• what: The authors demonstrate that depletion of the MKS2/TMEM216 and TMEM107 proteins induces constant deciliation of some cilia while depletion of either NPHP4 CEP290 or RPGRIP1L prevents Ca2+/EtOH deciliation. The authors show using super-resolution microscopy and transmission electron microscopy (TEM) that all 5 proteins localize with 9-fold symmetry at the distal part of . . .
  

   

  

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