Mll-af4 and a murinized pser-variant thereof are turning on the nucleolar stress pathway

HIGHLIGHTS

• who: Anna Lena Siemund from the (UNIVERSITY) have published the Article: MLL-AF4 and a murinized pSer-variant thereof are turning on the nucleolar stress pathway, in the Journal: (JOURNAL)
• what: This study provides new insights and a molecular explanation for the described differences between hMLL-hAF4 (not leukemogenic) and hMLL-mAf4 (leukemogenic). The authors investigated target gene transcription by performing MACE-Seq experiment. One of the many repetitive rRNA promoters was cloned to set up a new reporter system with which the authors aimed to investigate Pol I activity. This study provides also a . . .
  

   

  

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