Mobilized multipotent hematopoietic progenitors stabilize and expand regulatory t cells to protect against autoimmune encephalomyelitis

HIGHLIGHTS

  • who: Sarantis Korniotis from the University of Oxford, United Kingdom have published the article: Mobilized Multipotent Hematopoietic Progenitors Stabilize and Expand Regulatory T Cells to Protect Against Autoimmune Encephalomyelitis, in the Journal: (JOURNAL)

SUMMARY

    The promotion of Treg expansion also took place in_vivo, and accounted for the protection against spontaneous type 1 diabetes (TID) in Non Obese Diabetic (NOD) mice induced by adoptive transfer of as few as 10,000 mobilized MPP per mouse. Considerable efforts are being produced aiming at promoting expansion of Tregs in_vitro with IL-2, rapamycin, activation with anti . . .

     

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