Modeling adsorption, conformation, and orientation of the fis1 tail anchor at the mitochondrial outer membrane

HIGHLIGHTS

• who: Beytullah Ozgur and collaborators from the Institute of Biotechnology, University of Helsinki, Helsinki, Finland have published the research: Modeling Adsorption, Conformation, and Orientation of the Fis1 Tail Anchor at the Mitochondrial Outer Membrane, in the Journal: Membranes 2022, 12, 752. of /2022/
• what: The authors have used atomistic and coarse-grained molecular dynamics simulations to investigate the behavior of the Fis1(TA) at a lipid bilayer mimicking the surface of mitochondria.
• how: The results are consistent with a model in which Fis1p does not require a translocation machinery for insertion at mitochondria . . .
  

   

  

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