HIGHLIGHTS
- who: Luca Parca from the DepartmentUniversity of have published the article: Modeling cancer drug response through drug-specific informative genes, in the Journal: Scientific Reports Scientific Reports
- what: The authors show that gene_expression data can be analyzed to systematically select subsets of informative genes that can be used for the prediction of pan-cancer drug response in terms of IC50 (drug concentration that reduces cell viability by 50%). The authors explore the predictive power of known drug_targets, their close physical interactors and the pathways in which they are involved. A first attempt used functional linked . . .
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