Modeling human hsv infection via a vascularized immune-competent skin-on-chip platform

HIGHLIGHTS

• who: Sijie Sun from the Ethical statement The study protocol involving human specimens was approved by the University of Washington Institutional Review Board Committee (STUDY00002443), and written informed consents were obtained from all participantsStudy participants were , seropositive and , seronegative healthy individuals (n=20), who had a history of culture proven recurrent genital , disease. Both male (n=4) and female (n=16) participants, ages between , and , years old (average at, .4), were included. Three-millimeter punch biopsies were obtained during clinical symptomatic recurrences from active genital herpes lesion sites as described previously10, , . Control skin biopsies were taken from . . .
  

   

  

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