HIGHLIGHTS
- who: Amu00e9lie Rodrigues from the (UNIVERSITY) have published the research: Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue, in the Journal: (JOURNAL) of 20/07/2022
- what: The study provides insights into the use of iPSCderived cells and organoids for retinal disease modeling, with a phenotype related to mutations in splicing factors and in an effort to identify potential pathomechanisms of retinal degeneration.
- how: The same observation is made for the area and geodesic diameter of the cells (Supplementary Fig 4) which confirms this greater irregularity . . .
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