Modeling the effector – regulatory t cell cross- regulation reveals the intrinsic character of relapses in multiple sclerosis

HIGHLIGHTS

  • who: Nieves Vélez de Mendizábal and collaborators from the (UNIVERSITY) have published the Article: Modeling the effector - regulatory T cell cross- regulation reveals the intrinsic character of relapses in Multiple Sclerosis, in the Journal: (JOURNAL)
  • what: The authors enriched the model with reversible and irreversible tissue damage which aims to provide a comprehensible link between autoimmune activity and clinical relapses and active lesions in the magnetic resonances studies in patients with Multiple Sclerosis. The analysis shows that the weakness in this negative feedback between effector and regulatory Tcells allows the immune system to . . .

     

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