HIGHLIGHTS
- What: Developing and analyzing both discrete patch and continuous space models the authors explore how various attributes of daisy quorum drive affect the chance of modifying local population characteristics and the risk that transgenic elements expand beyond a target area. The authors show that this "fitness-valley construct" once established by drive can persist and modify local populations but its expansion to other populations is inhibited because the fitness-valley construct is unfit at low frequency. The aim of this paper is to model "daisy quorum drive" (Fig 1), a combined approach that links a self-exhausting . . .

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