Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

HIGHLIGHTS

• who: David C. Hay and collaborators from the Centre for Cardiovascular Science, University of Edinburgh, The Queen`s Medical Research Institute, Little France Crescent, Edinburgh , TJ, UK have published the research work: Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells, in the Journal: (JOURNAL) of 21/Nov/2022
• what: The authors show that HLCs derived from human ESCs retain the ability to form 5hmC, providing a non-neoplastic and renewable source of human cells for liver research. The authors show that HLC exposure to LPO induces an increase in cellular steatosis and . . .
  

   

  

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