HIGHLIGHTS
- who: Patricia G. Izquierdo and colleagues from the Editor:, United Kingdom have published the article: Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning, in the Journal: PLOS ONE of 12/08/2022
- what: The authors demonstrate that nematodes exhibit a cholinergic modulation in two different paradigms, the precondition to low doses of the drug and the chronic stimulation with high intoxicating concentrations. Since the efficiency of these medications is limited , the authors propose the investigation of plasticity-promoting mechanisms to identify other targets to mitigate against the effects of . . .
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