Modelling the modulation of cortical up-down state switching by astrocytes

HIGHLIGHTS

  • who: Lisa Blum Moyse and Hugues Berry from the , France, University of Lyon, France have published the research: Modelling the modulation of cortical Up-Down state switching by astrocytes, in the Journal: (JOURNAL) of July/21,/2022
  • what: The authors propose neural network models made of three populations of cells: excitatory neurons inhibitory neurons and astrocytes interconnected by synaptic and gliotransmission events to explore how astrocytes can control this phenomenon. The models show that the difference of signalling timescales between astrocytes and neurons (seconds versus milliseconds) can induce a regime where the frequency of gliotransmission . . .

     

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