Modelling time-varying covariates effect on survival via functional data analysis: application to the mrc bo06 trial in osteosarcoma

HIGHLIGHTS

  • who: Marta Spreafico from the (UNIVERSITY) have published the paper: Modelling time-varying covariates effect on survival via functional data analysis: application to the MRC BO06 trial in osteosarcoma, in the Journal: (JOURNAL)
  • what: In this work a Functional covariate Cox Model (FunCM) to study the association between time-varying processes and a time-to-event outcome is proposed. This approach has never been applied to osteosarcoma treatment and provides new insight in understanding the effect of chemotherapy dosis intensity on sarcoma in childhood cancer. Since the main focus of the work was to develop . . .

     

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