Modelling tools to characterize acetaminophen pharmacokinetics in the pregnant population

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  • who: Sofie A. M. Brookhuis and colleagues from the Department of Development and Regeneration, KU Leuven, Leuven, BelgiumErasmus Medical Center (MC), Department of Hospital Pharmacy, GD Rotterdam, The Netherlands Department of Medical Oncology, University Medical Center Groningen, University of Groningen have published the paper: Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population, in the Journal: Pharmaceutics 2021, 13, 1302. of 15/Nov/2020
  • what: Both the models show variability in the diagnostic plots, which could not be explained by the studied covariates. A limitation of this approach, compared to population PK modelling, is . . .

     

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