HIGHLIGHTS
- who: October and collaborators from the National Eye Institute (NIH), United States Department of Biochemistry and Molecular Genetics, RNA Bioscience Initiative, University of Colorado have published the article: Modi cation mapping by nanopore sequencing, in the Journal: (JOURNAL)
- what: Figure 4B provides one example workflow for the detection of pseudouridine modifications; however, after sequencing is complete, all remaining steps of this analysis have multiple software options available to choose from.
SUMMARY
By embedding the nanopore within a membrane with a constant voltage bias, an ionic current drives single stranded nucleic_acids through . . .
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