Modifiable risk factors of non-syndromic orofacial clefts: a systematic review

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SUMMARY

    Phenotypic description by LAHSHAL classification. According to Sakran et_al, the male gender is generally authors found that the male gender is a risk factor for CL/P and CL, while CP is morea protective fo. According to Sakran et_al, the male gender is generally frequent infactor females Ethnic differences coul. potentially influence the incidence of OFCs. Conversely, according to Martinelli et_al, the 677T allele of the MTHFR gene seemed to be protective against the occurrence of CL/P in the Asian population. In contrast, Roosendaal et_al found that periconceptional use of folate increases the . . .

     

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