Modular use of the uniquely small ring a of mersacidin generates the smallest ribosomally produced lanthipeptide

HIGHLIGHTS

• who: Jakob H. Viel and Oscar P. Kuipers from the University of Groningen have published the paper: Modular Use of the Uniquely Small Ring A of Mersacidin Generates the Smallest Ribosomally Produced Lanthipeptide, in the Journal: (JOURNAL) of June/29,/2022
• what: The smallest construct containing ring A of mersacidin has been determined to be the pentapeptide CTFAL.
• how: This result is in line with the observation that the distance of Asp-5 and Glu-3 to the Thr residue of ring A leads to a higher modification efficiency .
• future: While . . .
  

   

  

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