Modulating tumour metabolism enhances gold nanoparticle radiosensitisation in hpv-negative head and neck cancer

HIGHLIGHTS

  • who: Jie Feng from the School of Pharmacy, Queens University, Lisburn Road, BL, UK have published the Article: Modulating tumour metabolism enhances gold nanoparticle radiosensitisation in HPV-negative head and neck cancer, in the Journal: (JOURNAL)
  • what: The authors investigate the radiosensitising potential of AuNPs in combination with the complex III electron transport chain inhibitor using models of head and neck Results: AuNP intracellular accumulation occurred in a concentration-dependent manner and was not influenced by microenvironmental oxygen levels with citrate capped 15 nm AuNPs readily internalised accumulating primarily within the cytoplasmic compartment. The authors . . .

     

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