Modulation of immunosuppressive cells and noncoding rnas as immunotherapy in osteosarcoma

HIGHLIGHTS

  • who: Yidan Xia and colleagues from the National Institutes of Health (NIH), United States Changchun University of Chinese have published the Article: Modulation of immunosuppressive cells and noncoding RNAs as immunotherapy in osteosarcoma, in the Journal: (JOURNAL)

SUMMARY

    Immune cells such as lymphocytes and natural killer cells can effectively control tumour invasion, which can be suppressed by immunosuppressive cells such as myeloid-derived suppressor cells (MDSCs), regulatory T_cells (Tregs), and tumourassociated macrophages (TAMs). CAR-T_cell treatment offers a significant advancement in T-cell-based immunotherapy and is predicted to be a game changer . . .

     

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