Modulation of measles virus ntail interactions through fuzziness and sequence features of disordered binding sites

HIGHLIGHTS

  • who: Christophe Bignon and colleagues from the CNRS and Aix-Marseille Univ Laboratoire Architecture et Fonction des Macromolecules Biologiques (AFMB) have published the research: Modulation of Measles Virus NTAIL Interactions through Fuzziness and Sequence Features of Disordered Binding Sites, in the Journal: (JOURNAL)
  • what: Deletion studies have shown that the long, N-terminal fuzzy region of NTAIL inhibits the interaction with XD and hsp70.
  • how: Very different results were obtained with hsp70 .
  • future: The NTAIL N-terminal region could dampen the NTAIL/XD interaction at least in part by lowering the . . .

     

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