Modulation of the autophagic pathway inhibits hiv-1 infection in human lymphoid tissue cultured ex vivo

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  • who: Su00f2nia Pedreu00f1o-Lu00f3pez from the AIDS Research Institute have published the Article: Modulation of the autophagic pathway inhibits HIV-1 infection in human lymphoid tissue cultured ex vivo, in the Journal: Scientific Reports Scientific Reports of 19/04/2022
  • how: In this model a significant autophagy induction was observed after 24 h of rapamycin treatment which resulted in an increase in LC3I and LC3II (Fig 1A) and a higher LC3II/LC3I ratio compared to the untreated control (Fig 1B and Suppl Fig 1). The results are in agreement with in_vivo data where autophagy was . . .

     

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