HIGHLIGHTS
- who: Wei Chen and collaborators from the Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China have published the article: Modulation of the p38 MAPK Pathway by Anisomycin Promotes Ferroptosis of Hepatocellular Carcinoma through Phosphorylation of H3S10, in the Journal: Oxidative Medicine and Cellular Longevity of 24/Nov/2022
- what: Since the authors wanted to know how histone H3S10 is involved in anisomycin-induced HCC cell death, the authors focused on pathways associated with cell death. By detecting intracellular iron, LPO, and MDA, the study demonstrated that anisomycin could induce ferroptosis in HCC cells . . .
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