Modulations of the neuronal trafficking of tissue-type plasminogen activator (tpa) influences glutamate release

HIGHLIGHTS

• who: Alexandre Varangot from the (UNIVERSITY) have published the research work: Modulations of the neuronal trafficking of tissue-type plasminogen activator (tPA) influences glutamate release, in the Journal: (JOURNAL) of 15/Dec/2022
• what: The authors provide new inputs about the neuronal trafficking of tPA, thus contributing to a better understanding of its brain functions and dysfunctions. When the authors focused on the times spent by axonal vesicles in both anterograde and retrograde directions, V-tPA appeared predominantly retrograde while VAMP2- containing vesicles were largely anterograde (Fig 5A, S5B). The authors investigated the trafficking and . . .
  

   

  

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