Molecular alterations in sporadic and sod1-als immortalized lymphocytes: towards a personalized therapy

HIGHLIGHTS

  • who: Isabel Lastres-Becker and colleagues from the Instituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, Arturo Duperier, Madrid, SpainDepartment of Biochemistry, School of Medicine, Universidad Autónoma de Madrid, Arturo Duperier , have published the article: Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy, in the Journal: (JOURNAL)
  • what: To identify specific and common mechanisms for designing appropriate therapeutic interventions the authors focused on the SOD1-mutated (SOD1-ALS) versus sALS patients. The authors aimed to characterize at both cellular and molecular level, patientderived LCLs, with the ultimate goal . . .

     

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