Molecular and biochemical techniques for deciphering p53-mdm2 regulatory mechanisms

HIGHLIGHTS

  • who: Konstantinos Karakostis and colleagues from the Biochemistry-Molecular Biology, Faculty of Science, Universidad de la República, Iguá, Gdańsk, Poland have published the research work: Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms, in the Journal: Biomolecules 2021, 11, 36. of /2021/
  • what: In this review, the authors focus on well-studied mechanisms regulating the p53-MDM2 pathway, and on the experimental methodology that has been building up for past years for revealing the mechanism whereby p53 is activated during the DNA Damage Response (DDR), rather than list binding partners, which . . .

     

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