HIGHLIGHTS
- who: Yin Guan and colleagues from the University of Miami Health System, United States have published the research work: Molecular and clinicopathological characteristics of ERBB2 gene fusions in 32,131 Chinese patients with solid tumors, in the Journal: (JOURNAL)
- what: Considering the characteristics of the receptor tyrosine kinase, the authors focused on the ERBB2 fusions which contain the kinase domain. In the study , 19 ERBB2-X and 23 X-ERBB2 fusions were identified , and the other ERBB2-KD fusions` direction was uncertain. At the same time, since ERBB2 amplification mainly occurs in gastric cancer, colorectal . . .
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