HIGHLIGHTS
- who: Antonio Junior Lepedda from the Department of Biomedical Sciences, University of Sassari, Sassari, Italy have published the article: Molecular and pathobiological insights of bikunin/UTI in cancer, in the Journal: (JOURNAL)
- how: To address such issues the authors analyzed bikunin expression data across several types of tumors by using UALCAN proteogenomic analysis portal.
SUMMARY
Although bikunin cannot inhibit directly uPA activity, it exerts a down-regulation of uPA mRNA expression and protein secretion leading to an inhibition of both in_vitro and in_vivo tumor cell invasion and metastasis. Its protein moiety . . .
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