Molecular and pathological analyses of iars1-deficient mice: an iars disorder model

HIGHLIGHTS

• who: Masaki Watanabe and colleagues from the Laboratory of Laboratory Animal Science and Medicine, School of Veterinary Medicine, Kitasato University, Higashi-23, Towada, Japan have published the article: Molecular and Pathological Analyses of IARS1-Deficient Mice: An IARS Disorder Model, in the Journal: (JOURNAL)
• what: The findings of this study provide new perspectives for basic research mice carrying a hypomorphic mutation in IARS1 showed fatty liver at a preweaning age on IARS disorder.
• how: Hirano et_al identified a homozygous missense mutation (c.235G > C p.V79L) in exon 3 of the IARS1 gene . . .
  

   

  

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