Molecular and structural evolution of cytochrome p450 aromatase

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  • who: Giovanna Di Nardo et al. from the Department of Life Sciences and Systems Biology, University of Torino, via Accademia Albertina , have published the Article: Molecular and Structural Evolution of Cytochrome P450 Aromatase, in the Journal: (JOURNAL)
  • what: The authors investigate the molecular evolution of this unique and highly substrate-selective enzyme by means of structural sequence alignment and homology modeling shedding light on its key role in species conservation. A six-amino-acid insertion is present in the invertebrate sequence compared to all the other sequences analyzed (between M276 and D277 in human aromatase . . .

     

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