Molecular architecture of the augmin complex

HIGHLIGHTS

  • who: Clinton A. Gabel from the (UNIVERSITY) have published the article: Molecular architecture of the augmin complex, in the Journal: (JOURNAL)
  • what: The study shows that a combination of cryo-EM and advanced protein structure prediction can be harnessed to elucidate the structures of highly flexible, and dynamic protein complexes such as augmin.

SUMMARY

    The work highlights how cryo-EM, complemented by computational advances and CLMS, can elucidate the structure of a challenging protein complex and provides insights into the function of augmin in mediating microtubule branching nucleation. Microtubule branching depends . . .

     

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