Molecular basis for dna recognition by the maternal pioneer transcription factor foxh1

HIGHLIGHTS

  • who: Radoslaw Pluta from the (UNIVERSITY) have published the research work: Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1, in the Journal: (JOURNAL) of 10/Nov/2022
  • what: In the case of FoxA proteins, the analysis shows a slight enrichment for the Forkhead motif, which is not enriched in FoxH1 ChIPseq peaks (Supplementary Fig 1e).
  • how: The authors analyzed the FoxH1 interaction with the TGTTTATT site and with the canonical forkhead motif (TGTTTAC) for comparison with other FOX proteins although these TT motifs scored lower than GG/GT (GK . . .

     

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