HIGHLIGHTS
- who: Xuefei Guo from the (UNIVERSITY) have published the Article: Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560, in the Journal: (JOURNAL)
- what: The authors report the cryo-electron microscopy (cryo-EM) structures of PS1 and PS2containing u03b3-secretase complexes with and without MRK-560 at overall resolutions of 2.9-3.4 u00c5.
SUMMARY
The authors report the cryo-electron microscopy (cryo-EM) structures of PS1 and PS2containing γ-secretase complexes with and without MRK-560 at overall resolutions of 2.9-3.4 Å. MRK-560 occupies . . .
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