Molecular basis of ligand-dependent regulation of nadr, the transcriptional repressor of meningococcal virulence factor nada

HIGHLIGHTS

• who: Alessia Liguori and colleagues from the Italy, Centre, University of Florence, Florence, Italy, Institute of have published the paper: Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA, in the Journal: (JOURNAL) of April/22,/2016
• what: The studies provide detailed insights into how small molecule ligands such as hydroxyphenylacetate derivatives found in relevant host niches modulate the structure and activity of NadR by ‘conformational selection' of inactive forms. Although additional factors influence nadA expression, the authors focused on its regulation by NadR, the major mediator of . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.