Molecular characterization of cancer associated fibroblasts in prostate cancer

HIGHLIGHTS

  • who: Giovanni Vitale et al. from the Department of Medical Biotechnology and Translational Medicine (BIOMETRA), University of Milan, Cusano Milanino, Milan, Italy have published the article: Molecular Characterization of Cancer Associated Fibroblasts in Prostate Cancer, in the Journal: (JOURNAL)
  • what: The stromal component, as a source of prognostic information for metastatic disease progression, has received little attention, with most research focusing on tumor cell characteristics . The authors characterized PCAFs through the identification of differentially expressed genes between PCAFs and prostate non-cancer associated fibroblasts (PNAFs) isolated from normal adjacent tumor tissue or human benign prostate . . .

     

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