Molecular-docking-guided design, palladium-catalyzed synthesis and anticancer activity of paclitaxel-benzoxazoles hybrids

HIGHLIGHTS

  • who: Ting Jiang from the Department have published the article: Molecular-docking-guided design, palladium-catalyzed synthesis and anticancer activity of paclitaxel-benzoxazoles hybrids, in the Journal: Scientific Reports Scientific Reports
  • what: Next, the authors focused on synthesizing the paclitaxel-benzoxazoles hybrids.
  • future: Owing to the remarkable cytotoxicity 7a needs an in-depth investigation to improve in terms of reducing dose-dependent effect which might assist in the development of anticancer agents in the future.

SUMMARY

    It was believed that the simplified paclitaxel analogues with better antitumor activities could . . .

     

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