Molecular-genetic profiling and high-throughput in_vitro disease

HIGHLIGHTS

• who: Top from the Telethon Kids Institute, The University of Western Australia, Perth, Australia have published the paper: Molecular-genetic profiling and high-throughput in_vitro disease, in the Journal: (JOURNAL)
• what: The authors compared the drug response profiles and the genetic features of 12 NMC cell lines (HCC-2429 , PER-403 , PER-624 , PER-704 , P896-CL , TC797 , TY82 , RPMI2650 , 8645 , 10326 , 11060 and 14169 ). The authors therefore restricted the analysis to focus on genes affected by high-confidence deleterious variants (i.e. those from Figure 6A).
• how: The authors used a unique . . .
  

   

  

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