Molecular insights into mrna polyadenylation and deadenylation

HIGHLIGHTS

  • who: Junjie Liu et al. from the School of Life Science and Technology, ShanghaiTech University, Shanghai, China have published the Article: Molecular Insights into mRNA Polyadenylation and Deadenylation, in the Journal: (JOURNAL)
  • what: The catalytic activities of the endonuclease CPSF73/Yth1 in polyadenylation, and the deadenylases CAF1 and CCR4 in deadenylation are quite poor if they function as standalone enzymes [15,86].
  • future: More research is needed to figure out the exact mechanism. Structural research is required to figure out the interaction network of CF IIm and clarify its function in eukaryotic pre . . .

     

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