Molecular interaction of fibrinogen with zeolite nanoparticles

HIGHLIGHTS

  • who: Hossein Derakhshankhah et al. from the Nano Drug Delivery Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran have published the research: Molecular interaction of fibrinogen with zeolite nanoparticles, in the Journal: Scientific Reports Scientific Reports of 22/05/2018
  • how: The results indicated that fibrinogen has a strong and thermodynamically favorable interaction with zeolite nanoparticles in a non-cooperative manner. Simulation results showed that both E- and D-domain of fibrinogen are bound to the EMT zeolite NPs via strong electrostatic interactions and undergo structural changes leading to exposing normally buried sequences. The . . .

     

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