Molecular investigation of candidate genes for pyroptosis-induced inflammation in diabetic retinopathy

HIGHLIGHTS

  • who: Nan Wang from the Huazhong University of Science and Technology, China have published the article: Molecular investigation of candidate genes for pyroptosis-induced inflammation in diabetic retinopathy, in the Journal: (JOURNAL)
  • what: In the current study, 13 differentially expressed pyroptosis-related genes in diabetic retinopathy were identified by bioinformatics for the first time, and eight of the most critical genes were identified by PPI analysis. The authors confirmed that high glucose could upregulate the expression of caspase-3 and GSDME in the diabetic model, suggesting that CASP3-mediated pyroptosis is involved in the development . . .

     

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