Molecular mechanism of light-driven sodium pumping

HIGHLIGHTS

• who: Kirill Kovalev from the Université, Grenoble, FranceAachen University have published the Article: Molecular mechanism of light-driven sodium pumping, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The experiments showed that similar to the protein in detergent micelles and lipids, crystallized KR2 also forms characteristic K-, L/M- and O-states (Fig 1). This work shows that Na+ binds far from R109 and D251 (Fig 2f).
• how: The results showed that Q78 is the key residue which is likely to act as a gate for sodium flipping upon sodium passage (Q78L mutant . . .
  

   

  

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