HIGHLIGHTS
- What: This study demonstrated the efficacy and possible molecular mechanism of Hedyotis diffusa in the treatment of lung cancer at both clinical and experimental levels, and provided the basis and new ideas for the study of the molecular mechanism of H. diffusa in the treatment of LUAD. The shortcomings of the study compared to the study by Peng et_al are that the authors did not consider prescriptions, but rather looked at the effects of individual drugs (Wang et_al, 2022; Peng et_al, 2023). H. diffusa is an important component of TCM clinical anticancer prescription (Han et_al, 2020; Wazir . . .

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