Molecular mechanisms in genetic aortopathy-signaling pathways and potential interventions

HIGHLIGHTS

  • who: Charlotte Xue Dong and colleagues from the Faculty of Health and Medical Sciences, University of Sydney, Sydney, NSW, Australia have published the article: Molecular Mechanisms in Genetic Aortopathy-Signaling Pathways and Potential Interventions, in the Journal: (JOURNAL) of 16/01/2023
  • what: Multiple signaling pathways influence both EC and VSMC phenotype, often acting in synergy to either promote or inhibit cell proliferation and phenotype.
  • future: Future investigations addressing cell specific targeting reduced toxicity and also less intense treatment effects may hold promise for effective new medical treatments of thoracic aortic aneurysm. Potential . . .

     

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