Molecular probing of the hpv-16 e6 protein alpha helix binding groove with small molecule inhibitors

HIGHLIGHTS

• who: Anne Rietz et al. from the Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of have published the article: Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0149845]. February 25, 2016 of February/25,/2016
• how: The contribution of the HPV-16 E6 arginine mutations to compound binding was tested in the TSA (Fig 7A and 7B S2-S5 Figs and S2 Table). When the experimental results were compared with the MD . . .
  

   

  

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